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									Mei-Shin Shih:A 
									Surgeon, Master,and 
									Mentor 
									
									Qun Wang M.D.1  
									Chunsheng Wang M.D.2  Lijie Tan 
									M.D.1  Jia Fan M.D.3 
									
									1 
									Department of Thoracic 
									Surgery, Zhongshan Hospital of Fudan 
									University 
									
									2 
									Department of Cardiac 
									Surgery, Zhongshan Hospital of Fudan 
									University 
									
									3 
									Liver Cancer Institute, 
									Zhongshan Hospital of Fudan University 
									
									  
									
									
									Studying medicine 
									
									Dr. Mei-Shin Shih was 
									born on January 5, 1918 to a literary family 
									in Fuzhou City, Fujian Province. In his 
									early years China was being plagued by years 
									of fighting among factional warlords, and 
									people were living in misery. He studied 
									very hard and was determined to get enrolled 
									into the Shanghai Medical College, now an 
									affiliate to Fudan University. His name 
									appeared on the school’s admission list 
									published by Shun Pao newspaper on August 
									18, 1936. 
									
									After the Anti-Japanese 
									War broke out, the school had to be 
									relocated again and again across the country 
									and he finally graduated in 1943 and worked 
									at the department of surgery as an assistant 
									resident and teaching assistant. In 1946, he 
									returned to Shanghai, and served as senior 
									assistant resident at the Red Cross Hospital 
									(now the Huashan Hospital), and later he 
									went on to work at Zhongshan Hospital.
									 
									
									In 1947 Prof. Chia-ssu 
									Huang established the department of 
									cardiothoracic surgery in the Zhongshan 
									Hospital and Shi soon became his right arm. 
									Under Prof. Huang’s instructions, Shi 
									embarked on an extraordinary journey of 
									medical explorations. It’s worth mentioning 
									that Prof. Huang personally performed two 
									surgeries (appendectomy and phrenic nerve 
									blockage) for Mei-xin Shi. The inheritance 
									of Prof. Huang’s medical legacy to Shi was 
									marked by the opening of the 7th annual 
									conference of the Chinese Medical 
									Association in 1947, when the two masters 
									jointly published an important article - 
									Experience on Surgical Treatment for 
									Pulmonary Tuberculosis: A Preliminary Report. 
									This article was published on the Chinese 
									Medical Journal and later became 
									normative guidelines for Chinese thoracic 
									surgeons to treat tuberculosis. The 
									inheritance of their medical legacies later 
									became a much told tale. 
									
									Dr. Shi helped Prof. 
									Huang in the establishment of the department 
									of cardiothoracic surgery in Zhongshan 
									Hospital, and later he became director of 
									the department and head of Shanghai 
									Institute of Cardiovascular Diseases. Under 
									his leadership, Zhongshan Hospital has 
									developed into one of China’s largest and 
									most advanced diagnosis & treatment centers 
									of thoracic and cardiac diseases. 
									
									
									Innovations 
									
									Prof. Shi has been 
									treating cardiothoracic diseases for decades 
									and has dedicated his whole life to the 
									development of cardiothoracic surgery in 
									China. 
									
									In 1945 a US surgeon Leo 
									Eloesser, 19th President of the 
									American Association for Thoracic Surgery 
									(1936-37), was invited to China and make a 
									speech about the latest advances in the 
									surgical treatment of cardiothoracic 
									diseases. When talking about the surgery for 
									Tetralogy of Fallot, he joked to the 
									audience that he would cut off his head if 
									anyone else in the room could perform this 
									sophisticated surgery. 
									
									In the newly founded 
									China, the most sophisticated surgical 
									instruments were not availible from the 
									Western due to disembargoes. That made it 
									extremely difficult to carry out this 
									complicated surgery. In the first place, a 
									very tiny and specially curved needle must 
									be in place before the surgery can begin. 
									Even such a needle could not be produced in 
									China at that time.  
									
									Dr. Shih was determined 
									to make this kind of needle by himself. He 
									bought tiny crewel needles and heated them 
									on the alcohol lamp so that the needles 
									could bend. It’s easy saying than doing, 
									because quenched metals are prone to break 
									up. After numerous failed attempts in more 
									than ten days, he finally made a batch of 
									needles that could be used in the surgery. 
									He then used the needles to perform 
									surgeries on animals and gained confidence 
									after several successful practices. Early in 
									1953, a patient with Tetralogy of Fallot was 
									admitted in Zhongshan Hospital. After making 
									full preparations for the surgery, Dr. Shi 
									adopted new procedures and used the 
									self-made needles to perform the first 
									Blalock-Taussig shunt in China. 
									
									After successful 
									completion of the surgery on March 2, 1953, 
									Dr. Shih did neither make it public nor make 
									aggressive efforts to spread news about his 
									successful practice, because what he did was 
									not for personal gains. The surgery was not 
									known by the outside world as the first 
									Blalock-Taussig shunt for Tetralogy of 
									Fallot in China until the patient died 41 
									years later. When asked about this landmark 
									operation, Shi said there was no special 
									feeling after the surgery, but he indeed 
									felt a sense of relief for he did what was 
									once considered a mission impossible. 
									
									In addition to the first 
									Blalock-Taussig shunt for Tetralogy of 
									Fallot in China, he also performed the many 
									“firsts” in China’s history of 
									cardiothoracic surgery: resection of 
									pulmonary metastases (January 1948); primary 
									resection of lungs for the management of 
									empyema, thoracoplasty after lung resection, 
									ligation & division of the abberant right 
									subclavian artery, and substernal jejunal 
									interposition (1953); suturing and division 
									of the patent ductus arteriosus (1954); 
									primary radical treatment for the congenital 
									esophageal atresia and esophago-tracheal 
									fistula; and mitral commissurotomy via 
									interatrial groove through right thoracotomy 
									(1957); direct closure of atrial septal 
									defects under hypothermia (April 1958); 
									homograft repair of aortic arch aneurysm 
									(1959); direct repair of ruptured sinus of 
									Valsalva under cardiopulmonary bypass 
									(1960); resection of left ventricular 
									aneurysm under deep hypothermic 
									cardiopulmonary bypass, and mitral valve 
									repair under direct vision (1962); resection 
									of manubrium chondroma and allograft 
									transplantation for the cryopreserved 
									manubrium and bilateral sternoclavicular 
									joints (in cooperation with the Department 
									of Orthopedics) (1970);. 
									
									With his unique 
									innovations, Dr. Shi completed many 
									"impossible" missions for China. 
									
									Another extraordinary 
									contribution by him was the development of 
									artificial heart-lung machine. Due to 
									political reasons, Western countries barred 
									export of such machines into China at that 
									time. Prof. Shi came up with a bold idea of 
									independently developing the machine. He 
									drew schematics of the machine and brought 
									the drawings to machinery plants in Shanghai 
									to consult experts. After more than one year 
									of relentless efforts and 191 animal tests, 
									China’s first static vertical screen 
									artificial heart-lung machine finally rolled 
									off the production line. With this machine, 
									Zhongshan Hospital had carried out a series 
									of open heart surgeries since September 1959 
									and the safety of these surgeries was 
									substantially improved. These 
									domestically-made machines were later used 
									in many medical institutions across the 
									country and saved numerous lives. 
									 
									
									Given Prof. Shi’s 
									remarkable contributions, the Chinese 
									Medical Association’s Society of Surgery 
									decided in 1975 to dispatch him to attend 
									the 26th conference of the International 
									Society of Surgery at Edinburgh, UK. Only 
									three Chinese attended this conference.
									 
									
									
									Role model 
									
									In the 1950s, Mei-xin Shi 
									was the first to open training courses for 
									thoracic surgeons in China and a large 
									number of thoracic surgeons acquired skills 
									and expertise from these training programs.
									 
									
									Prof. Shi was president 
									of Shanghai First Medical College from 1978 
									to 1984. As a man of dedication, candor, 
									integrity and simplicity, he had been making 
									every effort to restore order at the college 
									disrupted during the ‘Cultural Revolution’. 
									As a mentor of postgraduates, he had been 
									tireless in teaching and trained roughly 300 
									thoracic surgeons from China as well as 
									Indonesia, Mongolia and Vietnam. 
									
									Prof. Shi has been a 
									rigorous scholar with many works to his 
									credit. He has published nearly 100 
									scientific articles. He was chief editor of 
									medical publications like Practical 
									Surgery, Illustrated Cardiothoracic 
									Surgery, Atlas of Vascular Surgery, 
									and Manual for Grassroot Doctors. 
									He 
									also participated in the compilation of 
									professional medical textbooks including 
									Surgery, James Shen’s Textbook of 
									Surgery, Chia-ssu Huang’s Textbook of 
									Surgery, Vascular Surgery, and 
									Cardiothoracic Surgery. He was nearly 90 
									years old when editing Practical Surgery, a 
									textbook that had been revised seven times. 
									He reviewed scripts of millions of 
									characters and carefully read every sentence 
									before making any revision. He would not 
									miss any mistake, even a punctuation mark or 
									a typo. He said even the slightest error was 
									not acceptable for a reference book that 
									every young doctor would have to use. 
									
									Prof. Shi was also deputy 
									chief editor of major dictionaries like 
									Cihai, Da Cihai, and Chinese Medical 
									Encyclopedia, and he was in charge of 
									reviewing the definition of medical terms.
									 
									
									What impressed us most is 
									Dr. Shih's care and support to younger 
									doctors. In January 2013 the Ministry of 
									Health planned to publish Color 
									Illustrations for Cardiothoracic Surgery, an 
									important book under the key national 
									publishing project (2011-2015). The 
									publishing house had already decided to name 
									Dr. Shi as chief editor, but he insisted 
									this honor should be granted to his student, 
									Prof. Chun-sheng Wang. He wrote an ebullient 
									preface for the book, saying ‘the book, with 
									exquisite pictures, accurate descriptions 
									and prominent practicality, will definitely 
									play a positive role in conducive to deeper 
									study on cardiothoracic diseases’. In the 
									preface he expressed a sincere hope that the 
									younger generation can really excel their 
									masters in terms of academic achievements. 
									
									
									Life in the late years 
									
									Dr. Shi has also spent a 
									colorful life in his late years. He set and 
									repeatedly renewed his own record of being 
									the oldest doctor joining in expert 
									consultations. He and his beloved wife, 
									Prof. Zhong-nian Chen, who is also a medical 
									professor, accompanied each other and led a 
									peaceful life in their final years. Their 
									residence was just a few meters away from 
									Zhongshan Hospital, and students of the 
									medical school had always met them on the 
									way between the hospital and their house.
									 
									
									Compared with doctors ‘in 
									the modern times’, Prof. Shi looked more 
									like a doctor of the past. He cares much 
									more about creation and giving than 
									receiving or self-consummation. Once there 
									was a proposal that he should apply to be an 
									academician of either the Chinese Academy of 
									Sciences or Chinese Academy of Engineering, 
									and his application, if submitted, stands a 
									good chance of being approved given his 
									reputation and contribution. However, he 
									flatly rejected the proposal. His rejection 
									is apparently unimaginable in today’s world. 
									This might be what is supposed to be for a 
									master of thoracic surgery. 
									
									Several months after his 
									wife passed away, Prof. Shi also left the 
									world he had been loving so deeply, with his 
									wisdom and his hands. Definitely, the legend 
									of the master continues, as the Memorial 
									Chia-ssu Huang Lecture will be held to pass 
									down the story between the two giants in 
									thoracic surgery in China, which was a deep 
									wish from Prof. Shi. A Chinese’s journal on 
									thoracic disease would be honored to have 
									their legend continue, and world widely 
									spread.  
									
									  
									
									
									The life of Dr. Mei-Shin Shih 
									 
									
									January 5, 1918, born in Fuzhou, Fujian 
									
									1933-1936, studied in Gezhi High School, 
									Fuzhou 
									
									1936-1943, studied at Shanghai School of 
									Medicine 
									
									1943, assistant resident and teaching 
									assistant at the Affiliated Hospital of 
									Shanghai Medical College  
									
									1948, surgeon and lecturer at Affiliated 
									Hospital of Shanghai Medical College 
									
									1950, medical officer during the Korean War 
									
									1951, helped Prof. Chia-ssu Huang establish 
									the department of cardiothoracic surgery 
									
									1954, Professor of surgery, director, 
									Department of Cardiothoracic Surgery at 
									Zhongshan Hospital, and head of Shanghai 
									Institute of Cardiovascular Diseases 
									
									1978-1984, president of Shanghai First 
									Medical College 
									
									January 10, 2014, passed away  
									  
									  
									Drs 
									Yaxing Shen, Hao Wang, Zhen Yang, and Weiguo 
									Ma contributed partly to the manuscript. 
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